Fig. 2 | Scientific Reports

Fig. 2

From: Integrated transcriptomic and metabolomic analyses reveal distinct energy metabolic signatures and functional properties of RPE cells under two culture conditions

Fig. 2

Transcriptomic profiling reveals divergent gene expression patterns associated with metabolic regulation in RPE cells cultured in B27 and KSR media. (A) Canonical RPE marker expression in 4-week cultured KSR- and B27-RPE cells; (B) Volcano plot of differentially expressed genes between the two groups; (C,D) GO enrichment analysis of upregulated genes in B27-RPE cells (C) and KSR-RPE cells (D); E: Heatmap of differentially expressed genes related to “fatty acid metabolism”(E), “glucose metabolism” (F) and metabolic regulatory pathways (G) of KSR- and B27-RPE cells.

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