Fig. 2 | Scientific Reports

Fig. 2

From: Tribolium castaneum with longer duration of tonic immobility have more variations corresponding to the human Parkinson’s disease genomic region

Fig. 2

Network of molecules associated with Parkinson’s disease. This network diagram depicts molecular interactions and expression changes related to Parkinson’s disease. The central node represents Parkinson’s disease (equivalent to Parkinson disease 16 (PARK16)), surrounded by nodes corresponding to associated genes. Node colors indicate expression levels: red for upregulation, green for downregulation, with color intensity reflecting the magnitude of change. Node shapes distinguish molecule types. Edges represent predicted molecular relationships; dashed lines indicate indirect interactions. Blue edges denote predicted inhibition, while gray edges indicate relationships with unspecified effects. Numbers in the upper left corner of each node show the number of detected isoforms or transcript variants for that molecule in the dataset. An asterisk following a gene name indicates that multiple identifiers in the dataset map to a single gene in the Global Molecular Network. Additionally, the nodes for ATP13A2 and PLA2G6 are linked to PARK9 and PARK14, respectively.

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