Table 1 Small variant genes involved in Parkinson’s disease in Tribolium castaneum strains with homologous human genes.
T. castaneum | SNV_InDel | Homologous protein ID (human protein) | Human Gene Symbol | E-value | % Identity | ||||
|---|---|---|---|---|---|---|---|---|---|
Protein ID | Gene ID | Gene name | Products (protein) | L-strain | S-strain | ||||
NP_258414.1 | 803,829 | COX1 | Cytochrome c oxidase subunit I | ✓ | ✓ | YP_003024028.1 | COX1 | 0 | 76 |
NP_001164199.1 | 100,142,317 | hsp68a | Heat shock protein 68a | ✓ | XP_011541100.1 | HSPA8 | 0 | 75 | |
NP_001164200.1 | 100,142,517 | hsp68b | Heat shock protein 68b | ✓ | XP_011541100.1 | HSPA8 | 0 | 75 | |
NP_001164310.1 | 661,125 | LOC661125 | Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | ✓ | NP_005994.2 | UQCRFS1 | 3E-108 | 70 | |
XP_008196617.1 | 657,039 | LOC657039 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X2 | ✓ | NP_004159.2 | SDHA | 0 | 78 | |
XP_008201665.1 | 655,618 | LOC655618 | NADH-quinone oxidoreductase subunit B 2 | ✓ | NP_077718.3 | NDUFS7 | 9.8E-105 | 76 | |
XP_015833401.1 | 100,142,620 | LOC100142620 | Heat shock cognate 71 kDa protein isoform X1 | ✓ | XP_011541100.1 | HSPA8 | 0 | 74 | |
XP_015833402.1 | 100,142,620 | LOC100142620 | Heat shock 70 kDa protein isoform X2 | ✓ | XP_011541100.1 | HSPA8 | 0 | 70 | |
XP_967271.1 | 655,618 | LOC655618 | NADH-quinone oxidoreductase subunit B 2 | ✓ | NP_077718.3 | NDUFS7 | 9.8E-105 | 76 | |
XP_968620.1 | 657,039 | LOC657039 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1 | ✓ | NP_004159.2 | SDHA | 0 | 77 | |
XP_969318.1 | 657,790 | LOC657790 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | ✓ | XP_016881271.1 | NDUFV2 | 1.9E-113 | 70 | |
XP_974442.1 | 663,293 | LOC663293 | Heat shock protein 70 A1 | ✓ | XP_011541100.1 | HSPA8 | 0 | 75 | |
