Table 2 Antioxidants and oxidative stress markers in heart of control and different treated rat groups.

From: Cardioprotective effects of curcumin and piperine against obesity induced oxidative stress in rats

Parameters

Groups

    

Control

DMSO

Cur + Pip

HFD

HFD + Cur+Pip

GPx (U/g)

     

 Mean ± SE

682.4 ± 6.933

680.2 ± 4.903

684.2 ± 4.620

428.4 ± 4.915a

595.0 ± 6.000ab

 % of change

     

  1

 

− 0.322

+ 0.263

− 37.221

− 12.807

  2

    

+ 38.888

SOD (U/g)

     

 Mean ± SE

185.0 ± 5.950

187.6 ± 7.461

182.0 ± 4.301

107.4 ± 6.911a

152.8 ± 4.079ab

 % of change

     

  1

 

+ 1.405

− 1.621

− 41.945

− 17.405

  2

    

+ 42.271

CAT (U/g)

     

 Mean ± SE

193.2 ± 9.107

192.4 ± 6.250

190.0 ± 5.301

92.40 ± 6.329a

140.2 ± 5.453ab

 % of change

     

  1

 

− 0.414

− 1.656

− 52.173

− 27.432

  2

    

+ 51.731

MDA (nmol/g)

     

 Mean ± SE

252.8 ± 12.54

250.4 ± 11.00

250.4 ± 6.218

567.2 ± 13.77a

367.8 ± 12.16ab

 % of change

     

  1

 

− 0.949

− 0.949

+ 124.367

+ 45.490

  2

    

− 35.155

NO (mmol/g)

     

 Mean ± SE

25.80 ± 2.782

26.20 ± 1.744

25.20 ± 2.267

88.00 ± 3.564a

42.20 ± 4.067ab

 % of change

     

  1

 

+ 1.550

− 2.325

+ 241.085

+ 63.565

  2

    

− 52.045

ROS (nmol/g)

     

 Mean ± SE

1.537 ± 0.06173

1.543 ± 0.02963

1.580 ± 0.08185

4.877 ± 0.069a

2.170 ± 0.097ab

 % of change

     

  1

 

+ 0.390

+ 2.797

+ 217.306

+ 41.184

  2

    

− 55.505

  1. Data are presented as mean ± SE (N = 6). a: Significant differences when compared to the control group (P ≤ 0.05). b: Significant differences when comparing HFD + Cur+Pip to the HFD group (P ≤ 0.05). (1%): Percentage change compared to the control group. (2%): Percentage change compared to the HFD group.
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