Table 1 IC50s for CPD-1, identified to be a highly selective inhibitor of human INPP5K.

From: Crystal structure of human INPP5K with an allosteric inhibitor reveals the structural basis for species specific potency

CPD-1

Human INPP5K

Hamster INPP5K

Guinea pig INPP5K

Mouse INPP5K

Rat INPP5K

Human SHIP2

Human PIPP

View full size image

2.9

8.2

59.0

 > 100

 > 100

 > 100

 > 100

Back to article page