Fig. 7 | Scientific Reports

Fig. 7

From: High-intensity interval training remodels perineuronal nets in the medial prefrontal cortex to drive microglial polarization and alleviate osteoarthritis pain

Fig. 7

PNN remodeling precedes microglial polarization. (A-D) Representative triple immunofluorescence staining images of the mPFC, showing PNN, Iba1, and iNOS (A), or PNN, Iba1, and Arg1 (C). Quantification of panel A is shown in (B), and quantification of panel C is shown in (D) (n = 6). Statistical methods used: One-way ANOVA. **p < 0.01. Data are presented as mean ± SD.

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