Table 5 Statistical analysis of the results obtained by the proposed method and the reported method for determination of BBL and MTK.

From: Eco-friendly RP-HPLC determination of bambuterol hydrochloride and montelukast sodium in tablet dosage with dissolution analysis

Value

Bambuterol HCL

Montelukast sodium

Proposed method

Reported Method16*

Proposed method

Reported Method16*

Mean

100.34

100.00

99.54

100.00

S.D

1.703

1.302

1.841

1.171

n

6

6

6

6

Variance

2.900

1.695

1.612

1.371

F value (5.05)a

1.71

-

1.17

-

Student’s t-test (2.228)a

0.388

-

0.071

-

  1. *Reported method was HPLC method using a C18 Phenomenex column (250 mm X 4.6 mm, 5 μm), and mobile phase consisted of methanol: acetonitrile: 0.1% trichloro acetic acid (80:10:10, v/v/v) at flow rate 1.0 ml/min and UV detection at 220 nm .
  2. a The numbers in parenthesis are the respective theoretical values at P = 0.05.
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