Table 1 Shows demographic characteristics and hemodynamic data of both groups. Continuous data represented as mean and standard deviation (SD), and categorical data as number and percentage (%).

Parameter	Sch-PAH (n = 41)			IPAH (n = 42)			P
Age (years) Gender Female	Mean/N	SD/%		Mean/N	SD/%		< 0.001 ^†
	50.4	12		34.45	9.71		< 0.001 ^†
	13	31.71		36	85.71		< 0.001 *
Male Presence of comorbidity	28	68.29		6	14.29
Male Presence of comorbidity	11	26.83		1	2.38		0.002*
Diabetes mellitus	2	4.88		0	0		0.24*
Cardiovascular disease	3	7.32		1	2.38		0.35*
Chest disease	3	7.32		0	0		0.03*
Hepatic disease (1 HBV, 2HCV, 2HCC) WHO FC FC-I	5	12.2		0	0		0.02 *
Hepatic disease (1 HBV, 2HCV, 2HCC) WHO FC FC-I	2	4.88		3	7.14		0.66*
FC-II	16 39.02			20 47.62			0.42*
FC-III	18		43.9	19		45.24	0.91*
FC-IV 6MWD (meters) Echocardiography PASP (mmHg)	5		12.2	0		0	0.007*
	296.4		82.2	300.5		96	0.83 ^†
	85.1		24.2	85.1		24.2	0.41^†
Dilated RA	39		95.12	37		88.1	0.24*
Dilated RV	39		95.12	39		92.86	0.66*
Dilated LA	18		43.9	7		16.67	0.006*
Pericardial effusion	4		9.76	6		14.29	0.52*
EF (%) Hemodynamic mRAP	66.5		6.13	68.11		7.94	0.35 ^†
EF (%) Hemodynamic mRAP	9.87		5.98	9.85		5.34	0.98^†
mPAP	54.9		11.8	56.9		16	0.55^†
CI	2.52		1.06	2.56		1.08	0.86^†
PVR	11.91		6.01	15		12.7	0.18^†
Svo2	60.69		8.74	62.6		11.2	0.41^†
PA dilatation (by Chest CT > 32 mm) Duration of illness in month (from the beginning of symptoms till time of diagnosis) Outcome Alive All-cause mortality Mono-Therapy	6		14.63	0		0	0.01*
	35.4		14.6	28.7		14.9	0.04^†
	34 7 5		82.93 17.07 12.2	37 5 1		88.1 11.9 2.38	0.51 0.08*

N, number; SD, standard deviation; †: Independent t-test, *: Chi square test, P < 0.05 considered significant.
HBV, hepatitis B virus; HCV, hepatitis C virus; HCC, hepatocellular carcinoma; PA, Pulmonary artery; Sch- PAH, Schistosomiasis-associated pulmonary arterial hypertension; IPHT, Idiopathic pulmonary arterial hypertension; FC, functional class; RA, right atrium; RV, right ventricle; LA, left atrium; EF, ejection fraction; 6MWD, 6 min’ walk distance.
mPAP, mean pulmonary artery pressure; mRAP, mean right atrial pressure; CI, cardiac index; PVR, pulmonary vascular resistance; SVo2, oxygen saturation in the mixed venous blood.
CT, computed tomography.

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