Table 2 Summary of experimental and predicted skin permeability coefficients of NIA.

From: Effect of pH on niacinamide skin permeation

 

Permeability coefficient (cm s−1)

 

pH 5.0

pH 7.4

Experiment (Human Skin)

13 ± 6 × 10–8

31 ± 8 × 10–8

Experiment (EpiDerm)

34 ± 9 × 10–8

54 ± 25 × 10–8

Theoretical prediction A (Eq. S1)

4.6 × 10–8

4.8 × 10–8

Theoretical prediction B (Eqs. S2-S5)

8.5 × 10–8

8.7 × 10–8

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