Table 4 Urinary 6-SMT levels and perinatal correlates in very preterm infants.

From: Urinary 6-sulfatoxymelatonin as a predictive biomarker for brain injury in very preterm infants

 

UM1

UM2

UM3

 

r/Z

P

r/Z

P

r/Z

P

GA

0.25

0.004*

0.31

< 0.001*

0.04

0.030*

BW

0.34

< 0.001*

0.36

< 0.001*

0.01

0.008*

MgSO₄

– 3.03

0.002*

– 2.13

0.033*

– 7.49

0.454

Gender

– 0.62

0.531

– 1.03

0.302

– 0.88

0.377

ACS

– 1.42

0.153

– 1.66

0.095

– 1.08

0.279

Acidosis

– 0.18

0.851

– 0.28

0.775

– 1.40

0.161

Asphyxia

– 0.89

0.370

– 1.62

0.103

– 3.17

0.751

Early infection

– 0.79

0.425

– 0.66

0.503

– 0.10

0.920

  1. * indicates statistical significance (p < 0.05). Statistical analyses were performed using the Mann-Whitney U test for categorical variables (e.g., MgSO4, gender) and Spearman’s correlation for continuous variables (e.g., GA, BW). Significant results are shown in bold.
  2. UM1, urinary 6-SMT on day 1; UM2, urinary 6-SMT on day 3; UM3, urinary 6-SMT on day 7.