Table 2 Comparison of aneurysm characteristics and blood test results among ruptured patients, unruptured patients, and healthy controls.

	R group (n=24)	U group (n=26)	Control (n=23)	p value
Aneurysm characteristics
Height, mm	5.0 [3.5, 6.3]	2.3 [1.7, 3.1]		< 0.001*
Neck, mm	3.0 [2.6, 3.9]	2.9 [2.3, 3.3]		0.25
Aspect ratio	1.5 [1.2, 1.7]	0.9 [0.6, 1.0]		< 0.001*
Bleb	23 (100)	2 (8.3)		< 0.001*
Location				0.001*
ICA	2 (8.3)	13 (50)
ACoA/ACA	6 (25.0)	3 (12)
MCA	3 (13)	7 (27)
PCoA	11 (45.8)	2 (7.7)
VA/BA	2 (8.3)	1 (3.8)
Blood test
LDL, mg/dL	122.0 [83.5, 154.0]	116.0 [104.3, 141.3]	116.5 [98.5, 130.3]	0.83
HDL, mg/dL	65.0 [58.3, 68.5]	68.0 [59.0, 75.0]	59.0 [54.3, 73.3]	0.52
TG, mg/dL	83.5 [65.0, 136.8]	107 [72.8, 180.0]	86.0 [63.3, 112.0]	0.52
CRP, mg/dL	0.05 [0.04, 0.13]	0.05 [0.04, 0.08]	0.04 [0.04, 0.08]	0.73
WBC, ´10³/μL	10.0 [6.6, 15.2]	5.0 [4.4, 5.6]	4.8 [4.4, 5.3]	< 0.001*
Hb, g/dL	14.4 [12.8, 14.9]	13.9 [13.1, 14.8]	14.3 [13.7, 15.1]	0.55
Plt, ´10³/μL	249 [188, 268]	251 [232, 276]	224 [214, 246]	0.16
Anti-SITH-1 antibody titer	1.32 [1.07, 2.14]	2.39 [1.68, 3.19]	1.39 [0.84, 1.98]	0.008*

ACA, Anterior cerebral artery; ACoA, Anterior communicating artery; Alb, Albumin;ALT, Alanine aminotransferase; AST, Aspartate aminotransferase; BA, Basilar artery; Cre, Creatinine; CRP, C-reactive protein; Hb, Hemoglobin; HbA1c, Hemoglobin A1c; HDL, High-density lipoprotein cholesterol; Ht, Hematocrit; ICA, Internal carotid artery; LDL, Low-density lipoprotein cholesterol; MCA, Middle cerebral artery; PCoA, Posterior communicating artery; Plt, Platelet count; SITH-1, Small protein encoded by the intermediate-stage transcript of HHV-6; T-Bil, Total bilirubin; TG, Triglycerides; TP, Total protein; UN, Urea nitrogen; VA, Vertebral artery; WBC, White blood cell count. *p < 0.05. Unless otherwise indicated, values represent the number of aneurysms (%) or median and interquartile range. Not all percentages total 100% due to rounding.

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