Table 3 Antiviral activity of the tested samples.
Virus | Sample | IC50 (µg/mL) | CC50 (µg/mL) | SI |
|---|---|---|---|---|
HAV | Ethanolic extract | Weak | 270.33 ± 11.04 | Inactive |
Ethyl Acetate fraction | 51.23 ± 0.96 | 201.16 ± 4.38 | 3.923 | |
Methylene chloride fraction | Weak | 419.04 ± 12.36 | Inactive | |
Butanol fraction | 24.42 ± 1.09 | 176.2 ± 4.31 | 7.21 | |
Hexane fraction | Weak | 161.98 ± 2.53 | Inactive | |
Acyclovir | 14.75 ± 0.3 | 297.39 ± 3.47 | 20.16 | |
HSV-1 | Ethanolic extract | 93.88 ± 2.85 | 270.33 ± 11.04 | 2.88 |
Ethyl Acetate fraction | 14.75 ± 0.33 | 201.16 ± 4.38 | 13.63 | |
Methylene chloride fraction | Weak | 419.04 ± 12.36 | Inactive | |
Butanol fraction | 13.23 ± 0.33 | 176.2 ± 4.31 | 13.32 | |
Hexane fraction | 29.74 ± 0.41 | 161.98 ± 2.53 | 5.45 | |
Acyclovir | 3.07 ± 0.15 | 138.54 ± 1.85 | 45.12 | |
HSV-2 | Ethanolic extract | Weak | 270.33 ± 11.04 | Inactive |
Ethyl Acetate fraction | 25.41 ± 1.81 | 201.16 ± 4.38 | 7.19 | |
Methylene chloride fraction | Weak | 419.04 ± 12.36 | Inactive | |
Butanol fraction | 15.15 ± 0.28 | 176.2 ± 4.31 | 11.63 | |
Hexane fraction | 47.37 ± 1.12 | 161.98 ± 2.53 | 3.41 | |
Acyclovir | 6.95 ± 0.36 | 138.54 ± 1.85 | 19.93 |
