Table 2 Univariable Cox proportional hazards analysis for overall survival (OS) and cancer-specific survival (CSS).
Variable | OS HR (95% CI) | P | CSS HR (95% CI) | P |
|---|---|---|---|---|
Age (years) | ||||
≤ 60 (ref) | 1 (ref) | — | 1 (ref) | — |
> 60 | 1.07 (0.81–1.43) | 0.622 | 0.92 (0.68–1.25) | 0.605 |
Race | ||||
White (ref) | 1 (ref) | — | 1 (ref) | — |
Black | 1.01 (0.73–1.39) | 0.943 | 1.01 (0.71–1.43) | 0.972 |
Other | 0.85 (0.53–1.36) | 0.491 | 0.95 (0.58–1.55) | 0.834 |
Sex | ||||
Male (ref) | 1 (ref) | — | 1 (ref) | — |
Female | 0.90 (0.67–1.22) | 0.501 | 0.86 (0.62–1.19) | 0.363 |
Differentiation grade | ||||
I/II (ref) | 1 (ref) | — | 1 (ref) | — |
III/IV | 1.46 (0.97–2.19) | 0.068 | 1.71 (1.09–2.70) | 0.020 |
Unknown | 1.32 (0.88–1.98) | 0.173 | 1.39 (0.88–2.19) | 0.157 |
SEER summary stage | ||||
Localized (ref) | 1 (ref) | — | 1 (ref) | — |
Regional | 1.41 (0.97–2.07) | 0.075 | 1.48 (0.96–2.28) | 0.074 |
Distant | 2.75 (1.87–4.04) | < 0.001 | 3.20 (2.09–4.89) | < 0.001 |
Unknown | 1.30 (0.82–2.05) | 0.259 | 1.42 (0.86–2.34) | 0.169 |
Radiotherapy | ||||
No (ref) | 1 (ref) | — | 1 (ref) | — |
Yes | 0.70 (0.52–0.93) | 0.014 | 0.73 (0.54–1.00) | 0.047 |
Chemotherapy | ||||
No (ref) | 1 (ref) | — | 1 (ref) | — |
Yes | 1.02 (0.78–1.33) | 0.892 | 1.14 (0.86–1.52) | 0.373 |
Surgery | ||||
No (ref) | 1 (ref) | — | 1 (ref) | — |
Yes | 0.34 (0.26–0.45) | < 0.001 | 0.34 (0.25–0.46) | < 0.001 |
