Fig. 14
From: In vitro and in vivo evaluation of oleuropein loaded hyalurosomes for diabetic foot ulcer healing
Histopathological Evaluation of Skin across Experimental Groups (H&E X400). (a) Normal control—GP: high power view showing average keratinized epidermis (black arrow), average pilosebaceous units (red arrow), and average collagen (blue arrow). (b) DFU—GP: high power view in deep dermis showing large scar tissue composed of excess active fibroblasts (black arrow), excess collagen (red arrow), and excess inflammatory infiltrate (blue arrow). (c) Fucidin cream—GP: high power view in upper dermis showing small scar tissue composed of inactive fibroblasts (black arrow), scanty thin collagen (red arrow), and scattered inflammatory infiltrate (blue arrow). (d) OLE-HLs gel—GP: high power view showing intact epidermis (black arrow), small hypocellular scar tissue composed of few inactive fibroblasts (red arrow), and few thin collagen (blue arrow). (e) OLE gel—GP: high power view showing intact epidermis (black arrow), small hypocellular scar tissue showing few thick collagen (red arrow), and few inflammatory infiltrate (blue arrow).
