Fig. 15
From: In vitro and in vivo evaluation of oleuropein loaded hyalurosomes for diabetic foot ulcer healing
Immunohistochemical Expression of NF-κB in Skin Tissue (Immunostain, X400). (a) Normal Control-GP: Skin view showing negative reactivity (0) for NF-KB (red arrow). (b) DFU—GP: Skin view showing marked reactivity (+++) for NF-KB (red arrow). (c) Fucidin cream—GP: Skin view showing mild reactivity (+) for NF-KB (red arrow). (d) OLE-HLs gel—GP: Skin view showing mild reactivity (+) for NF-KB (red arrow). (e) OLE gel—GP: Skin view showing moderate reactivity (++) for NF-KB (red arrow).The criteria for assigning these scores were based on the intensity and distribution of the immunostaining observed under a microscope. Specifically:
