Table 1 Baseline demographic and clinical characteristics of the KD and control groups.

From: Real-world outcomes of ketogenic diet therapy in children with drug-resistant epilepsy in a prospective cohort study

 

Control group (n = 63)

KD group (n = 73)

P

Age of onset (year)

0.92(0.42–2.25)

0.80(0.55–1.26)

0.84

Gender

  

0.99

Male (%)

60.3(38/63)

60.3(44/73)

 

Female (%)

39.7(25/63)

39.7(29/73)

 

Etiology

  

0.06

Hereditary/Metabolic (%)

23.8(15/63)

39.7(29/73)

 

Structural (%)

47.6(30/63)

26.0(19/73)

 

Infection/Immunity (%)

4.8(3/63)

4.1(3/73)

 

Unknown (%)

23.8(15/63)

30.1(22/73)

 

Baseline seizure frequency

90.00(13.00–96.00)

90.00(90.00–99.00)

0.43

Seizure type

  

0.14

Focal (%)

27.3(38/139)

20.3(32/158)

 

Spasms (%)

25.9(36/139)

34.8(55/158)

 

Tonic (%)

3.6(5/139)

8.9(14/158)

 

Clonic (%)

2.2(3/139)

3.2(5/158)

 

Myoclonic (%)

10.8(15/139)

8.9(14/158)

 

Absence (%)

9.4(13/139)

3.8(6/158)

 

Tonic-clonic (%)

10.1(14/139)

10.8(17/158)

 

Tonic-spasms (%)

7.2(10/139)

4.4(7/158)

 

Status epilepticus (%)

3.6(5/139)

5.1(8/158)

 

No. Seizure type (IQR)

2.00(1.00–3.00)

2.00(1.00–3.00)

0.64

Disease duration (year)

2.50(0.75-4.00)

2.40(1.90–3.65)

0.18

Types of ASMs (species)

4.00(3.00–5.00)

4.00(3.00–5.00)

0.46

Change of Weight (Kg)

0.50(0.00-1.50)

1.00(0.50–1.83)

0.24

Change of Height (cm)

3.00(2.00–6.00)

4.00(2.00–7.00)

0.25

  1. The total number of KD groups does not add up to 158, and the total number of control groups does not add up to 139, because some participants do not know that there are two or more seizure types.