Table 2 Significant differences in lipids between the IS and Control groups.

From: Lipidomic profiling identifies key pathways and a 5-lipid panel with high diagnostic efficacy for ischemic stroke

Lipids

m/z

RT (min)

log2(FC)

VIP

P value

PE(16:0/16:1)

688.49

12.09

-2.52

1.49

< 0.001

DAG(16:0/20:4)

634.50

13.37

-2.16

1.71

< 0.001

TAG48:3-FA16:0

810.53

16.64

-1.81

1.07

< 0.001

PE(P-18:0/22:4)

778.60

13.93

1.77

2.00

< 0.001

TAG48:3-FA14:0

810.53

16.54

-1.76

1.04

< 0.001

PA(18:0/22:4)

751.53

13.21

1.67

2.00

< 0.001

TAG48:3-FA16:1

812.53

17.10

-1.55

1.11

< 0.001

TAG48:2-FA14:0

810.53

16.99

-1.49

1.04

< 0.001

PG(20:0/16:1)

775.55

10.69

-1.29

1.36

< 0.001

DCER(24:1)

650.90

15.35

-1.26

1.23

< 0.001

TAG54:3-FA20:2

818.53

17.44

-1.17

1.57

< 0.001

PE(P-18:1/22:4)

776.60

13.11

1.15

1.88

< 0.001

DAG(18:2/20:4)

658.50

12.46

-1.10

1.51

< 0.001

DAG(16:1/18:2)

608.50

12.69

-1.09

1.45

< 0.001

PE(P-18:1/18:2)

724.50

12.70

1.08

1.91

< 0.001

PE(P-16:0/20:5)

720.50

11.78

1.08

1.13

< 0.001

PC(14:0/16:1)

704.55

10.65

-1.07

1.17

< 0.001

TAG56:4-FA18:0

820.53

17.68

-1.06

1.46

< 0.001

PE(P-18:0/22:6)

774.50

13.11

1.034

1.52

< 0.001

  1. Note: The log₂FC was determined based on the ratio of lipid abundance in IS group relative to the healthy control group. A positive log₂FC value indicates upregulation of the lipid species in the IS group, whereas a negative value indicates downregulation.