Fig. 6 | Scientific Reports

Fig. 6

From: Cycloastragenol attenuates osteoarthritis by restoring chondrocyte senescence via the NRF2/NF-κB signaling axis

Fig. 6The alternative text for this image may have been generated using AI.

CAG mitigates senescence through NRF2 activation. (A–D) Western blot analysis and quantification of senescence key markers (p53, CDKN1A, CDKN2A) in chondrocytes under si-NRF2 transfection treatments (See Supplementary Materials for original blots). n = 3. (E,F) Representative images and quantitative analysis of β-galactosidase staining. n = 3, bar = 50 μm. (G,H) Representative images and quantitative analysis of EdU staining. n = 3, bar = 50 μm. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

Back to article page