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Biomechanical evaluation of X-ray permeable CF/PEEK composite versus conventional titanium alloy for tibial external fixation plates: a finite element analysis
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  • Published: 14 March 2026

Biomechanical evaluation of X-ray permeable CF/PEEK composite versus conventional titanium alloy for tibial external fixation plates: a finite element analysis

  • Shuaiyi Wang1,2 na1,
  • Zuodong Zhao3 na1,
  • Lin An1,2,
  • Ning Ni1,2,
  • Jingwei Zhang1,2,
  • Qing Yan4 &
  • …
  • Jianming Chen1,2 

Scientific Reports , Article number:  (2026) Cite this article

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We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Engineering
  • Materials science
  • Medical research

Abstract

This study aimed to evaluate the mechanical performance of CF/PEEK composite plates for external fixation through finite element analysis (FEA), and to explore the impact of different screw placement patterns on fixation stability. A proximal tibial fracture model treated with external fixation was constructed using FEA. Longitudinal loading was applied to simulate walking stress, with additional internal and external rotational torques to mimic load-bearing movement. Mechanical responses of titanium alloy and CF/PEEK plates were compared under three loading conditions: longitudinal, longitudinal with internal rotation, and longitudinal with external rotation. Screw alignment was also varied between linear and non-linear configurations to assess its biomechanical influence. Compared to titanium alloy group, the linear CF/PEEK plate exhibited a mild increase in displacement of 0.232–0.386 mm (8.23–11.14%), accompanied by a substantial reduction in plate stress of 46.03–80.84%. At the fracture site, interfragmentary displacement increased slightly by 0.105–0.132 mm (5.56–6.74%), while fracture-site stress increased by 3.119–18.029 MPa (18.30–63.20%). The non-linear CF/PEEK plate demonstrated a similar biomechanical performance, with no significant differences compared with the linear configuration. For external plate fixation, CF/PEEK represents a promising alternative to conventional titanium alloy plates. By allowing an acceptable level of local micromotion, CF/PEEK plates significantly reduce stress in the plate and screws while increasing stress transfer at the fracture site. This load-sharing behavior may mitigate stress shielding associated with traditional metallic plates and thereby promote early biological fracture healing.

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Data availability

The datasets used and/or analysed during the current study available from the corresponding author on reasonable request.

References

  1. Court-Brown, C. M. & Caesar, B. Epidemiology of adult fractures: A review. Injury [Internet]. 2006 Aug 1 [cited 2025 Jul 31];37(8), 691–7 (2025). Available from: https://www.sciencedirect.com/science/article/pii/S0020138306003238?via%3Dihub

  2. Cong, B. & Zhang, H. Acute compartment syndrome in tibial fractures: A meta-analysis. BMC Musculoskelet Disord. 26(1), 329. https://doi.org/10.1186/s12891-025-08586-z (2025).

    Google Scholar 

  3. Yoon, Y. C. et al. Staged Fixation with Respect to Soft Tissue in Tibial Plateau Fractures with Acute Compartment Syndrome: Correlation Analysis of Complications. Clin. Orthop. Surg. 16(6), 854–862 (2024).

    Google Scholar 

  4. Gaudinez, R. F., Mallik, A. R. & Szporn, M. Hybrid External Fixation of Comminuted Tibial Plateau Fractures. Clin. Orthop. Relat. Res. [Internet]. 328, 203–210. (1996). Available from: https://journals.lww.com/clinorthop/fulltext/1996/07000/hybrid_external_fixation_of_comminuted_tibial.32.aspx

  5. Tripathy, S. K. et al. External fixation versus open reduction and internal fixation in the treatment of Complex Tibial Plateau Fractures: A systematic review and meta-analysis. Acta. Orthop. Traumatol.Turc. 55(5), 444–456 (2021).

    Google Scholar 

  6. Janssen, S. J. & Kloen, P. Supercutaneous locking compression plate in the treatment of infected non-union and open fracture of the leg. Arch. Orthop. Trauma. Surg. 142(11), 3201–3211. https://doi.org/10.1007/s00402-021-04104-7 (2022).

    Google Scholar 

  7. Bologna, F. A., Audenino, A. L. & Terzini, M. Bone plates runout prediction through tensile strength and geometric properties for regulatory mechanical testing. Ann. Biomed. Eng. 52(2), 239–249. https://doi.org/10.1007/s10439-023-03363-2 (2024).

    Google Scholar 

  8. Egol, K. A., Kubiak, E. N., Fulkerson, E., Kummer, F. J. & Koval, K. J. Biomechanics of Locked Plates and Screws. J. Orthop. Trauma. [Internet]. 18(8), (2004). Available from: https://journals.lww.com/jorthotrauma/fulltext/2004/09000/biomechanics_of_locked_plates_and_screws.3.aspx

  9. Zhang, S. et al. Experimental testing of fracture fixation plates: A review. Proc. Inst. Mech. Eng. H. 236(9), 1253–1272. https://doi.org/10.1177/09544119221108540 (2022).

    Google Scholar 

  10. Stoffel, K., Dieter, U., Stachowiak, G., Gächter, A. & Kuster, M. S. Biomechanical testing of the LCP – how can stability in locked internal fixators be controlled? Injury [Internet]. 2003 Nov 1 [cited 2025 Jul 31];34(SUPPL. 2), 11–9 (2009). Available from: https://www.sciencedirect.com/science/article/pii/S0020138303003796?via%3Dihub

  11. Kurtz, S. M. & Devine, J. N. PEEK biomaterials in trauma, orthopedic, and spinal implants. Biomaterials [Internet]. 2007 Nov 1 [cited 2025 Jul 31];28(32), 4845–69 (2007). Available from: https://www.sciencedirect.com/science/article/pii/S0142961207005467?via%3Dihub

  12. Hu, Z., He, J., Chen, W., Liu, W., Ding, J. & He, C. et al. High-performance carbon fiber reinforced polyether-ether-ketone composite pellets 3D-Printed via screw-extrusion additive manufacturing. Compos. Sci. Technol. [Internet]. 2024 Feb 8 [cited 2025 Jul 31];246, 110362 (2024). Available from: https://www.sciencedirect.com/science/article/pii/S0266353823004566?via%3Dihub

  13. Bologna, A. F. et al. In silico evaluation of the primary stability of acetabular revision cups: Standard versus locking screws. J. Biomech. Eng. https://doi.org/10.1115/1.4068226 (2025).

    Google Scholar 

  14. Ceddia, M., Pesare, E., Solarino, G., Lamberti, L. & Trentadue, B. Biomechanical Comparison of Titanium and CFR-PEEK Intramedullary Nails Using Finite Element Analysis. J. Compos. Sci. 9(11), 576 (2025).

    Google Scholar 

  15. Beirami, S., Nikkhoo, M., Hassani, K. & Karimi, A. A comparative finite element simulation of locking compression plate materials for tibial fracture treatment. Comput. Methods Biomech. Biomed. Eng. 24(10), 1064–1072. https://doi.org/10.1080/10255842.2020.1867114 (2021).

    Google Scholar 

  16. Zhang, J. et al. External fixation using locking plate in distal tibial fracture: A finite element analysis. Eur. J. Orthop. Surg. Traumatol. 25(6), 1099–1104. https://doi.org/10.1007/s00590-015-1604-7 (2015).

    Google Scholar 

  17. Ng, B. W. et al. Finite element analysis and clinical evaluation of cross locking external fixator configuration for distal third tibia fracture. Sci. Rep. 15(1), 13310. https://doi.org/10.1038/s41598-025-97090-4 (2025).

    Google Scholar 

  18. Ye, X., Luo, J., Chen, P., Wei, X. & Liu, S. Finite element analysis of the stability of tibiofibular fractures treated with various combinations of external fixators. BMC. Musculoskelet. Disord. 26(1), 304. https://doi.org/10.1186/s12891-025-08530-1 (2025).

    Google Scholar 

  19. Tian, R. et al. Prevalence and influencing factors of nonunion in patients with tibial fracture: Systematic review and meta-analysis. J. Orthop. Surg. Res. 15(1), 377. https://doi.org/10.1186/s13018-020-01904-2 (2020).

    Google Scholar 

  20. Ye, Z. et al. Study on the relationship between the timing of conversion from external fixation to internal fixation and infection in the treatment of open fractures of extremities. J. Orthop. Surg. Res. 16(1), 662. https://doi.org/10.1186/s13018-021-02814-7 (2021).

    Google Scholar 

  21. Schmidt, A. H. The Impact of Compartment Syndrome on Hospital Length of Stay and Charges Among Adult Patients Admitted With a Fracture of the Tibia. J. Orthop. Trauma. [Internet]. 25(6), 355–357 (2011). Available from: https://journals.lww.com/jorthotrauma/fulltext/2011/06000/the_impact_of_compartment_syndrome_on_hospital.7.aspx

  22. Ahmad, M. A., Sivaraman, A., Zia, A., Rai, A. & Patel, A. D. Percutaneous locking plates for fractures of the distal tibia: Our experience and a review of the literature. J. Trauma. Acute. Care. Surg. [Internet]. 72(2) (2012). Available from: https://journals.lww.com/jtrauma/fulltext/2012/02000/percutaneous_locking_plates_for_fractures_of_the.53.aspx

  23. Zhang, J., Ebraheim, N. A., Li, M., He, X., Liu, J. & Zhu, L. et al. External Fixation Using a Locking Plate: A Reliable Way in Treating Distal Tibial Fractures. J. Orthop. Trauma. [Internet]. 29(11), (2015). Available from: https://journals.lww.com/jorthotrauma/fulltext/2015/11000/external_fixation_using_a_locking_plate__a.15.aspx

  24. Su, H., Zhong, S., Ma, T., Wu, W., Lu, Y. & Wang, D. Biomechanical study of the stiffness of the femoral locking compression plate of an external fixator for lower tibial fractures. BMC Musculoskelet Disord [Internet]. 24(1), 39 (2023). Available from: https://doi.org/10.1186/s12891-023-06150-1

  25. Makelov, B. et al. Single-Stage Externalized Locked Plating for Treatment of Unstable Meta-Diaphyseal Tibial Fractures. J. Clin. Med. 12(4), 1600 (2023).

    Google Scholar 

  26. Blažević, D. et al. Comparison between external locking plate fixation and conventional external fixation for extraarticular proximal tibial fractures: a finite element analysis. J. Orthop. Surg. Res. 17(1), 16 (2022).

    Google Scholar 

  27. Fang, S. et al. Finite element analysis comparison of Type 42A2 fracture fixed with external titanium alloy locking plate and traditional external fixation frame. J. Orthop. Surg. Res. 18(1), 815 (2023).

    Google Scholar 

  28. Liu, S. et al. A novel external fixation for treating tibial fractures: a finite element and biomechanical study. J. Orthop. Surg. Res. 20(1), 319 (2025).

    Google Scholar 

  29. Fisher, J. S., Kazam, J. J., Fufa, D. & Bartolotta, R. J. Radiologic evaluation of fracture healing. Skeletal. Radiol. 48(3), 349–61. https://doi.org/10.1007/s00256-018-3051-0 (2019).

    Google Scholar 

  30. Govaert, G. A. M., Kuehl, R., Atkins, B. L., Trampuz, A., Morgenstern, M. & Obremskey, W. T. et al. Diagnosing Fracture-Related Infection: Current Concepts and Recommendations. J. Orthop. Trauma. [Internet]. 34(1), (2020). Available from: https://journals.lww.com/jorthotrauma/fulltext/2020/01000/diagnosing_fracture_related_infection__current.3.aspx

  31. Flowers, D. W., McCallister, E., Christopherson, R. & Ware, E. The Safety and Effectiveness of Early, Progressive Weight Bearing and Implant Choice after Traumatic Lower Extremity Fracture: A Systematic Review. Bioengineering. 9, 750 (2022).

    Google Scholar 

  32. Panayotov, I. V., Orti, V., Cuisinier, F. & Yachouh, J. Polyetheretherketone (PEEK) for medical applications. J. Mater. Sci. Mater. Med. [Internet]. 27(7), 118 (2016). Available from: https://doi.org/10.1007/s10856-016-5731-4

  33. Krätzig, T. et al. Carbon fiber–reinforced PEEK versus titanium implants: An in vitro comparison of susceptibility artifacts in CT and MR imaging. Neurosurg. Rev. 44(4), 2163–2170. https://doi.org/10.1007/s10143-020-01384-2 (2021).

    Google Scholar 

  34. Yu, W., Li, X., Ma, X. & Xu, X. Biomechanical analysis of inclined and cantilever design with different implant framework materials in mandibular complete-arch implant restorations. J. Prosthet. Dent. [Internet]. 2022 May 1 [cited 2025 Jul 31];127(5), 783.e1–783.e10 (2022). Available from: https://www.sciencedirect.com/science/article/pii/S0022391322001433?via%3Dihub

  35. Müther, M., Lüthge, S., Gerwing, M., Stummer, W. & Schwake, M. Management of Spinal Dumbbell Tumors via a Minimally Invasive Posterolateral Approach and Carbon Fiber–Reinforced Polyether Ether Ketone Instrumentation: Technical Note and Surgical Case Series. World Neurosurg. [Internet]. 2021 Jul 1 [cited 2025 Jul 31];151, 277–283.e1 (2021). Available from: https://www.sciencedirect.com/science/article/pii/S1878875021006094?via%3Dihub

  36. Guo, Y., Chen, C., Zhang, S., Ren, L., Zhao, Y. & Guo, W. Mediation of mechanically adapted TiCu/TiCuN/CFR-PEEK implants in vascular regeneration to promote bone repair in vitro and in vivo. J. Orthop. Translat. [Internet]. 2022 Mar 1 [cited 2025 Jul 31];33, 107–19 (2025). Available from: https://www.sciencedirect.com/science/article/pii/S2214031X22000122?via%3Dihub

  37. Yang, Z., Guo, W., Yang, W., Song, J., Hu, W. & Wang, K. Polyetheretherketone biomaterials and their current progress, modification-based biomedical applications and future challenges. Mater. Des. [Internet]. 2025 Apr 1 [cited 2025 Jul 31];252, 113716 (2025). Available from: https://www.sciencedirect.com/science/article/pii/S0264127525001364?via%3Dihub

  38. Theivendran, K., Arshad, F., Hanif, U. K., Reito, A., Griffin, X. & Foote, C. J. Carbon fibre reinforced PEEK versus traditional metallic implants for orthopaedic trauma surgery: A systematic review. J. Clin. Orthop. Trauma. [Internet]. 2021 Dec 1 [cited 2025 Jul 31];23, 101674 (2025). Available from: https://www.sciencedirect.com/science/article/pii/S0976566221005580?via%3Dihub

  39. Laux, C. J., Hodel, S. M., Farshad, M. & Müller, D. A. Carbon fibre/polyether ether ketone (CF/PEEK) implants in orthopaedic oncology. World J. Surg. Oncol. 16(1), 241. https://doi.org/10.1186/s12957-018-1545-9 (2018).

    Google Scholar 

  40. Perren, S. M. Current concepts of internal fixation of fractures. Manual Inter. Fix. 63–77 (1980).

  41. Torstrick, F. B., Safranski, D. L., Burkus, J. K., Chappuis, J. L., Lee, C. S.D. & Guldberg, R. E. et al. Getting PEEK to Stick to Bone: The Development of Porous PEEK for Interbody Fusion Devices. Tech. Orthop. [Internet]. 32(3), (2017). Available from: https://journals.lww.com/techortho/fulltext/2017/09000/getting_peek_to_stick_to_bone__the_development_of.5.aspx

  42. Chen, Z. et al. Polyetheretherketone implants with hierarchical porous structure for boosted osseointegration. Biomater. Res. 27(1), 61. https://doi.org/10.1186/s40824-023-00407-5 (2023).

    Google Scholar 

  43. Tarallo, L., Mugnai, R., Adani, R., Zambianchi, F. & Catani, F. A new volar plate made of carbon-fiber-reinforced polyetheretherketon for distal radius fracture: Analysis of 40 cases. J. Orthop. Traumatol. 15(4), 277–283. https://doi.org/10.1007/s10195-014-0311-1 (2014).

    Google Scholar 

  44. Hu, X. et al. Laser direct-write sensors on carbon-fiber-reinforced poly-ether–ether–ketone for smart orthopedic implants. Adv. Sci. 9(11), 2105499. https://doi.org/10.1002/advs.202105499 (2022).

    Google Scholar 

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Funding

Supported by the Agricultural and Social Development Science and Technology Project of Yinzhou District, Ningbo City (2020AS0034); Ningbo No.6 Hospital Science and Technology Program (2023002); Ningbo Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation (2024L004).

Author information

Author notes
  1. Shuaiyi Wang and Zuodong Zhao have contributed equally to the work.

Authors and Affiliations

  1. Department of Trauma, Trauma Orthopedic Center, Ningbo No.6 Hospital Affiliated to Ningbo University, Ningbo, 315040, Zhejiang, China

    Shuaiyi Wang, Lin An, Ning Ni, Jingwei Zhang & Jianming Chen

  2. Ningbo Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation, Ningbo, Zhejiang, China

    Shuaiyi Wang, Lin An, Ning Ni, Jingwei Zhang & Jianming Chen

  3. Department of Oral Health Sciences-Orthodontics, KU Leuven and Service of Dentistry, University Hospitals Leuven, Leuven, Belgium

    Zuodong Zhao

  4. School of Biological and Chemical Engineering, NingboTech University, Ningbo, China

    Qing Yan

Authors
  1. Shuaiyi Wang
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Contributions

S.W. and Z.Z. wrote the manuscript text. L.A., N.N. and J.Z. constructed the finite element models and performed the simulations. Q.Y. analyzed the data and assisted with figure preparation. J.C. supervised the project and revised the manuscript. All authors reviewed and approved the final manuscript.

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Correspondence to Jianming Chen.

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Wang, S., Zhao, Z., An, L. et al. Biomechanical evaluation of X-ray permeable CF/PEEK composite versus conventional titanium alloy for tibial external fixation plates: a finite element analysis. Sci Rep (2026). https://doi.org/10.1038/s41598-026-43182-8

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  • Received: 12 August 2025

  • Accepted: 02 March 2026

  • Published: 14 March 2026

  • DOI: https://doi.org/10.1038/s41598-026-43182-8

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Keywords

  • Carbon fiber reinforced polyetheretherketone
  • External fixation
  • Finite element
  • Tibia fracture
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