Fig. 7 | Scientific Reports

Fig. 7

From: Natural genetic variation impacts complement inhibitory activity of PFam54 orthologs of Asian Borrelia bavariensis

Fig. 7

PFam54 Clade IV orthologs of Asian B. bavariensis facilitates serum resistance in a gain-of-function B. garinii strain. Survival of B. garinii G1 containing vectors encoding for BGA66NT24 (a), BGA67bJHM1114 (b), BGA68NT24 (c), BGA68bNT24 (d), BGA71NT24 (e), BGA71bJHM1114 (f), and G1 carrying the empty shuttle vector (g) in 50% NHS (filled circles) or in 50% hiNHS (open circles) was monitored by dark-field microscopy. Motile cells were counted at 0, 2, 4 and 6 h. At least three independent biological replicates were conducted for treatments with NHS and two independent treatments with hiNHS. Error bars indicate ± SD. For all plots, abbreviations refer to: NHS, non-immune human serum, hiNHS, heat-inactivated NHS.

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