Fig. 6 | Scientific Reports

Fig. 6

From: Hot melt extruded Kyungohkgo attenuates skeletal muscle atrophy by downregulating the FOXO3a/MuRF-1/atrogin-1 axis

Fig. 6The alternative text for this image may have been generated using AI.

Protective effects of KOG and HOG3 administration in rats with skeletal muscle atrophy. (a) Scheme of Dexa-induced skeletal muscle atrophy animal model. (b) Body weight was measured every three days. (c) Representative image of soleus muscle from each experimental group. (d) Weight of soleus muscle was measured for each experimental group. All results are presented as mean ± SD. ##p < 0.01 vs. the Control group; **p < 0.01, *p < 0.05 vs. the Dexa group. (e) Soleus muscle and gastrocnemius muscle were stained with H&E and Masson’s trichrome. The quantitative analyses were measured with (e): myofiber portion in soleus muscle (f), fibrosis area in soleus muscle (g), and myofiber portion in gastrocnemius muscle (h). Kyungohkgo, KOG; HME-processed KOG, HOG3; dexamethasone, Dexa.

Back to article page