Fig. 2 | Scientific Reports

Fig. 2

From: A digital twin framework for forensic reconstruction of alcohol intake via fast and slow metabolite kinetics

Fig. 2

Model agreement to the BAC and UAC data. The solid line is the best model fit (simultaneous agreement to all estimation data), the shaded area is the model uncertainty, the error bars is the standard error of the mean (SEM), and the ‘x’ notations indicate the reported individual data points. The model (shaded area) describes the dynamics of the A-J) blood alcohol concentration (BAC), K-T) urine alcohol concentration (UAC). All experiments includes a first drink of beer with a 0.51 g/kg dose of ethanol, consumed in 4 periods of 10 min over 60 min, and a second drink of varying doses, 0.25 g/kg (blue), 0.51 g/kg (purple), or 0.85 g/kg (red), composed of either; whiskey (A, E, I, K, O, S), vodka (B, F, J, L, P, T), beer (C, G, M, Q), or wine (D, H, N, E). The second drink was consumed over 15 min (low dose) or 30 min (medium and high dose). The periods where the drinks are consumed are indicated by the black bar over the x-axis. Meals were consumed after the start (300 kcal) of the session and 180 min into (500 kcal) the study.

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