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Development, validation and psychometric evaluation of the Plagiarism and Research Ethics Questionnaire (PRE-Q) among pharmacy students in Karachi, Pakistan
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  • Published: 02 April 2026

Development, validation and psychometric evaluation of the Plagiarism and Research Ethics Questionnaire (PRE-Q) among pharmacy students in Karachi, Pakistan

  • Sadia Shakeel1,
  • Humera Ishaq2,
  • Tahmina Maqbool3,
  • Hina Rehman4,
  • Muhammad Ali5,
  • Azfar Athar Ishaqui6,
  • Samreen Aziz7,
  • Halima Sadia8,
  • Safila Naveed9,
  • Saira Azhar7 &
  • …
  • Shazia Jamshed10,11 

Scientific Reports , Article number:  (2026) Cite this article

We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Education
  • Psychology

Abstract

Plagiarism is one of the most pressing challenges faced by higher education institutions, compromising academic integrity and negatively impacting the quality and credibility of scientific research. Therefore, this study aimed to assess undergraduate pharmacy students’ knowledge, attitudes, and practices regarding research ethics and plagiarism using the Plagiarism and Research Ethics Questionnaire (PRE-Q). This multi-centric, cross-sectional study aimed to validate the developed PRE-Q among final-year pharmacy students from different universities in Karachi, Pakistan. Internal consistency was assessed using Cronbach’s alpha, and principal component analysis (PCA) with Varimax rotation was conducted for data interpretability and reduce cross-loadings. Sampling adequacy and item correlations were confirmed using the KMO and Bartlett’s tests of sphericity. Key predictors of student practices were identified using binary logistic regression and decision tree analysis. The response rate of the study was 72.1%. Female respondents comprised 73.5% (n = 480) of the sample, with a mean age of 22.3 ± 0.82 years. The cut-off value for good KAP and experience was defined as achieving  ≥ 70% scoring across all the constructs. Good knowledge was observed in 26.4% (n = 173) respondents , while only 7% (n = 46) displayed a positive attitude towards plagiarism. The majority of students, 67% (n = 438) demonstrated good practices,  despite their limited involvement in research activities. Only 11% (n = 72) respondents had attended courses or workshops on ethics or responsible conduct of research. The most frequently reported reasons for plagiarism among students were academic pressure (n = 119, 18.2%), followed by lack of time (n = 103, 15.7%) and lack of knowledge (n = 89, 13.6%). The findings indicate that the PRE-Q is a valid and reliable tool for assessing research ethics and plagiarism related constructs.  The outcomes revealed patterns in plagiarism-related practices and highlighted the key predictors that may guide the development of targeted educational and policy interventions.

Data availability

The datasets used during the study are available from the corresponding author upon reasonable request.

Abbreviations

PRE-Q:

Plagiarism and Research Ethics Questionnaire

KMO:

Kaiser-Meyer-Olkin

CHAID:

Chi-squared automatic interaction detection

SDG:

Sustainable Development Goal

COPE:

Committee on Publication Ethics

LMS:

Learning management systems

STROBE:

Strengthening the Reporting of Observational Studies in Epidemiology

PCA:

Principal component analysis

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Author information

Authors and Affiliations

  1. Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Dow College of Pharmacy, Dow University of Health Sciences, Karachi, 74200, Pakistan

    Sadia Shakeel

  2. Shaheed Mohtarma Benazir Bhutto Medical College, Lyari, Karachi, 75660, Pakistan

    Humera Ishaq

  3. Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, Madinat al-Hikmah, Hakim Mohammed Said Road, Karachi, 74600, Pakistan

    Tahmina Maqbool

  4. Department of Pharmacy Practice, Institute of Pharmaceutical Sciences, Jinnah Sindh Medical University, Karachi, 75510, Pakistan

    Hina Rehman

  5. Department of Pharmaceutics and Pharmacy Practice, Faculty of Pharmacy, Salim Habib University, Karachi, 74900, Pakistan

    Muhammad Ali

  6. Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, 61421, Saudi Arabia

    Azfar Athar Ishaqui

  7. Faculty of Pharmacy, Iqra University, Karachi, 75500, Pakistan

    Samreen Aziz & Saira Azhar

  8. Department of Pharmacy Practice, Faculty of Pharmacy, Jinnah University for Women, Karachi, 74600, Pakistan

    Halima Sadia

  9. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Karachi, Karachi, 75270, Pakistan

    Safila Naveed

  10. Department of Pharmacy Practice, School of Pharmacy, IMU (Former International Medical University), Kuala Lumpur, 57000, Malaysia

    Shazia Jamshed

  11. Department of Pharmacy Practice, Shifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan

    Shazia Jamshed

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Contributions

SS, HI, TM, HR: Conception, Study design, Data collection, Data interpretation, Manuscript writing. MA, AA, SA: Data analysis, interpretation. SN, HS: Data collection, interpretation. SA, SJ: Supervision, Validation, Project administration. All authors reviewed the manuscript.

Corresponding author

Correspondence to Sadia Shakeel.

Ethics declarations

Competing interests

The authors declare no competing interests.

Ethics approval

The study was approved by the Ethical Review Committee of Hamdard University, Karachi, Pakistan (Reference No: ERC-FOP-2024-019). All methods were performed in accordance with the relevant guidelines and regulations. The study was conducted in accordance with the principles of the Declaration of Helsinki. The students were explained about the scope of study and their written consent was obtained. The questionnaire included a consent statement, and respondents were able to proceed only after clicking the “I Agree” button.

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Cite this article

Shakeel, S., Ishaq, H., Maqbool, T. et al. Development, validation and psychometric evaluation of the Plagiarism and Research Ethics Questionnaire (PRE-Q) among pharmacy students in Karachi, Pakistan. Sci Rep (2026). https://doi.org/10.1038/s41598-026-44299-6

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  • Received: 02 September 2025

  • Accepted: 10 March 2026

  • Published: 02 April 2026

  • DOI: https://doi.org/10.1038/s41598-026-44299-6

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Keywords

  • Plagiarism
  • Research ethics
  • Pharmacy students
  • Knowledge
  • Attitude
  • Pakistan
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