Fig. 4 | Scientific Reports

Fig. 4

From: Differential microRNA expression profiles and predicted miRNA–mRNA regulatory networks in human macrophage-like cells infected with Leishmania infantum

Fig. 4The alternative text for this image may have been generated using AI.

Predicted interactions between differentially expressed miRNAs and dysregulated target genes. Panel A and panel B refer to networks in cholesterol metabolism, at 24 h and 48 h, respectively, while panel C and panel D refer to the lipid biosynthetic process at 24 h and 48 h, respectively. The miRNAs are depicted as circular nodes and mRNAs as square nodes. Node fill color reflects the log₂ fold-change, with color gradients corresponding to the magnitude of expression changes. Larger nodes represent elements with a higher number of interactions.

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