Fig. 5

Spatial patterns captured by HET. Regional HET effect size maps comparing MSA subtypes and PD at baseline and 12-month follow-up are shown. The colors indicate effect size for significant regions after multiple comparison correction. Warm colors indicate higher regional HET in MSA than PD, and cool colors indicate lower regional HET in MSA than PD. Uncolored regions are not significant. The color bar reflects Cohen’s d and not HET values.