Table 3 Larvicidal activity for novel benzo[h]quinoline derivatives against Culex pipiens larvae, 48 h post-treatment.
Compds. | LC25 (µg/mL) (aF.l. at 95%) | LC50 (µg/mL) (aF.l. at 95%) | LC90 (µg/mL) (aF.l. at 95%) | bSlope ± SE | cX2 | dP | Relative potency |
|---|---|---|---|---|---|---|---|
4 | 3.10 (2.43–3.79) | 9.74 (7.98–12.31) | 85.87 (55.20- 158.68) | 1.35 ± 0.12 | 5.95 | 0.20 | 5.08 |
5 | 0.74 (0.49–1.01) | 2.49 (1.99–3.04) | 24.67 (17.59–39.10) | 1.28 ± 0.16 | 0.74 | 0.94 | 19.89 |
7 | 0.65 (0.42–0.89) | 2.16 (1.70–2.65) | 21.15 (15.27–32.95) | 1.29 ± 0.18 | 1.35 | 0.85 | 22.93 |
8 | 1.12 (0.79–1.47) | 3.74 (3.06–4.53) | 36.41 (25.26–59.98) | 1.29 ± 0.14 | 1.05 | 0.90 | 13.24 |
9 | 0.50 (0.31–0.71) | 1.61 (1.24–1.99) | 14.48 (10.72–21.79) | 1.34 ± 0.12 | 1.10 | 0.89 | 30.76 |
10 | 1.29 (0.91–1.67) | 4.42 (3.62–5.40) | 45.86 (30.87–79.16) | 1.26 ± 0.13 | 1.04 | 0.90 | 11.20 |
11 | 0.51 (0.31–0.74) | 1.83 (1.39–2.29) | 20.25 (14.21–33.30) | 1.22 ± 0.12 | 0.72 | 0.94 | 27.06 |
12 | 0.85 (0.57–1.15) | 3.02 (2.42–3.70) | 33.27 (22.85–55.93) | 1.23 ± 0.11 | 0.87 | 0.92 | 16.40 |
14 | 1.97 (1.46–2.50) | 6.87 (5.61–8.59) | 73.44 (46.79- 138.07) | 1.24 ± 0.14 | 2.48 | 0.64 | 7.20 |
16 | 2.46 (1.88–3.07) | 8.22 (6.72–10.35) | 81.22 (51.73- 152.53) | 1.28 ± 0.17 | 3.66 | 0.45 | 6.02 |
18 | 1.55 (1.12–1.99) | 5.33 (4.37–6.55) | 55.57 (36.67–98.88) | 1.26 ± 0.13 | 2.28 | 0.68 | 9.29 |
Temephos | 17.20 (13.92–20.74) | 49.53 (40.57–62.99) | 369.25 (240.32- 669.81) | 1.46 ± 0.13 | 6.06 | 0.19 | 1 |
