Table 2 Effect of ATRA and /or ACR on epididymal sperm count and percent of sperm motility. The effects of ACR and/or ATRA on sperm parameters. Data are mean ± SD; N = 10.a Significant from CTR. b Significant from DMSO. c Significant from ACR. d Significant from ATRA at P < 0.05, one-way ANOVA followed by post-hoc Tukey's test. One-way ANOVA revealed significant treatment effects on sperm count [F(4, 45) = 28.84, p < 0.0001] and sperm motility [F(4, 45) = 32.05, p < 0.0001].
From: ATRA-mediated RAR-α activation attenuates acrylamide-induced testicular toxicity
Group | Sperm count x 106 (mean +/- SD) | Sperm motility (%) (mean +/- SD) |
|---|---|---|
CTR | 358.3 +/- 45.46 | 86.13 +/- 3.02 |
DMSO | 329.2 +/- 44.66 | 81 +/- 9.5 |
ACR | 182.5 +/- 38.31 a | 39.92 +/- 7.24 a |
ATRA | 456.7 +/- 50.07 a,b,c | 85.41 +/- 5.63 a |
ATRA+ACR | 345.8 +/- 74.73 c,d | 70.76+/-6.26 a,b,c |