Table 1 The IC₅₀ and selectivity index values obtained for the SB1 and SB2 compounds.

From: Synthesis, characterization, and anticancer potency of sulfadiazine salicylaldehyde-based Schiff bases

Cancer cells

Normal cells

Compound

HCT116

MCF-7

HepG2

A549

T24

WI-38

IC₅₀ (µg/mL)

SI

IC₅₀ (µg/mL)

SI

IC₅₀ (µg/mL)

SI

IC₅₀ (µg/mL)

SI

IC₅₀ (µg/mL)

SI

IC₅₀ (µg/mL)

SB1

90.01 ± 0.12

3.66

66.27 ± 1.14

4.97

240.08 ± 3.83

1.37

91.5 ± 2.06

3.6

192.28 ± 1.12

1.71

329.61 ± 3.2

SB2

48.65 ± 2.12

4.84

59.61 ± 1.59

3.95

120.53 ± 2.62

1.95

68.56 ± 1.60

3.43

216.13 ± 0.70

1.09

235.41 ± 1.83

5-Fu

3.6 ± 0.33

3.72

5.13 ± 0.39

2.61

7.06 ± 0.6

1.89

6.94 ± 0.61

1.93

6.68 ± 0.22

2.0

13.4 ± 0.28

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