Table 1 Patients and treatment characteristics
Parameters | N (n = 1512) | % | SPM (%) |
|---|---|---|---|
Age | Median = 55 years (range: 14–87 years) | ||
Gender | |||
Male | 1285 | 84.9 | 105 (6.9) |
Female | 227 | 15 | 25 (1.7) |
Primary site | |||
Oropharynx | 1300 | 86 | 108 (7.2) |
Larynx | 105 | 6.9 | 13 (0.9) |
Nasopharynx | 87 | 5.8 | 6 (0.4) |
Sinonasal | 12 | 0.8 | 1 (0.1) |
Oral cavity | 8 | 0.5 | 2 (0.1) |
T category | |||
T1 | 396 | 26.2 | 28 (1.9) |
T2 | 520 | 34.4 | 53 (3.5) |
T3 | 310 | 20.5 | 30 (2.0) |
T4 | 231 | 15.3 | 16 (1.1) |
Tx | 55 | 3.6 | 3 (0.2) |
N category (all except nasopharynx) | |||
N0 | 172 | 11.4 | 17 (1.1) |
N1 | 183 | 12.1 | 19 (1.3) |
N2a | 132 | 8.7 | 8 (0.5) |
N2b | 574 | 38 | 51 (3.4) |
N2c | 219 | 14.5 | 17 (1.1) |
N3 | 101 | 6.7 | 8 (0.5) |
Nx | 44 | 2.9 | 4 (0.3) |
N category (nasopharynx) | |||
N0 | 16 | 1.1 | 0 |
N1 | 22 | 1.5 | 19 (1.3) |
N2 | 37 | 2.5 | 3 (0.2) |
N3 | 12 | 0.8 | 0 |
AJCC stage | |||
I | 61 | 4 | 7 (0.5) |
II | 104 | 6.9 | 10 (0.7) |
III | 234 | 15.5 | 25 (1.7) |
IV | 1113 | 73.6 | 88 (5.8) |
Smoking status at diagnosis | |||
Current | 368 | 24.3 | 42 (2.8) |
Ex-smoker (≥10-pack years) | 408 | 27 | 48 (3.2) |
Ex-smoker (<10-pack years) | 199 | 13.2 | 17 (1.1) |
Never smoker | 537 | 35.5 | 23 (1.5) |
Radiotherapy technique | |||
3D conformal | 172 | 11.4 | 18 (1.2) |
IMRT | 1340 | 88.6 | 112 (7.4) |
Radiation dose | Median = 6996 cGy (range: 5710–7600 cGy) | ||
Number of radiotherapy fractions | Median = 33 (range: 28–64) | ||
Induction chemotherapy | |||
Yes | 446 | 29.5 | 32 (2.1) |
No | 1066 | 70.5 | 98 (6.5) |
Concurrent chemotherapy | |||
Yes | 1005 | 66.5 | 89 (5.9) |
No | 507 | 33.5 | 41 (2.7) |
