Table 2 Multivariate analysis for the risk of development of SPM over time after index cancer

From: Risk of second primary malignancies in head and neck cancer patients treated with definitive radiotherapy

Parameters

Risk ratio

95% confidence interval

p-value

Age

17.79

4.6–68.4

< 0.0001

Sex (male)

0.7

0.47–1.14

0.16

Smoking status (current or ex > 10)

2.14

1.47–3.16

< 0.0001

AJCC stage

1.1

0.42–3.14

0.81

Induction chemotherapy (yes)

1.96

1.25–3.02

0.004

Concurrent chemotherapy (yes)

1.46

0.97–2.24

0.08

  1. P-values <0.05 are considered significant