Fig. 3: CD161+ T cell subsets have stronger cytotoxicity and proliferative capacity. | npj Precision Oncology

Fig. 3: CD161+ T cell subsets have stronger cytotoxicity and proliferative capacity.

From: The identification and functional analysis of CD8+PD-1+CD161+ T cells in hepatocellular carcinoma

Fig. 3: CD161+ T cell subsets have stronger cytotoxicity and proliferative capacity.

a CD161+ and CD161− two subsets of CD8+PD-1+ T cells. b, c Volcanic and heat map showing the differential expression. d GO enrichment analysis and proteins interaction (e) secretion level of IFN-γ, TNF-α, IL-2,GNLY, PRF, and GZMB in indicated subsets of T cells. Mononuclear cells were isolated from human HCC tumor region (T) and the surrounding non-tumor region (N) areas and stimulated with PMA+ Ionomycin+ for 4.5 h. Then, the cells were subjected to staining with indicated markers. f Potential regulation mechanism.

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