Table 1 Characteristics of 5 patients with COVID-19 and colorectal cancer and 20 matched patients with COVID-19 without cancer.
Characteristics | No. of patients (%) | P value | |
|---|---|---|---|
Colorectal cancer (n = 5) | Without cancer (n = 20) | ||
Sex | Â | Â | 1 |
 Female | 2 (40) | 8 (40) |  |
 Male | 3 (60) | 12 (60) |  |
Age | Â | Â | 1 |
 >65 y | 3 (60) | 14 (70) |  |
 ≤65 y | 2 (40) | 6 (30) |  |
Comorbid conditions | |||
 0 | 1 (20) | 4 (20) | 1 |
 1 | 3 (60) | 13 (65) |  |
 2 | 0 (0) | 0 (0) |  |
 3 | 1 (20) | 3 (15) |  |
Type of comorbid condition | |||
 Diabetes | 1 (20) | 5 (25) | 1 |
 Hypertension | 3 (60) | 11 (55) | 1 |
 Coronary heart disease | 1 (20) | 2 (10) | 0.504 |
 Cerebrovascular disease | 0 (0) | 1 (5) | 1 |
 Renal disease | 1 (20) | 3 (15) | 1 |
 Liver disease | 0 (0) | 0 (0) | / |
TNM disease stage | |||
 I | 2 (40) | / |  |
 II | 2 (40) | / |  |
 III | 1 (20) | / |  |
Tumor site | |||
 Colon | 1 (20) | / |  |
 Rectum | 4 (80) | / |  |
Laboratory findings | |||
 White blood cell count, <4 × 109/L | 1 (20) | 7 (35) | 1 |
 Lymphocyte count, <0.8 × 109/L | 4 (80) | 4 (20) | 0.023 |
 Neutrophil count, <1.8 × 109/L | 1 (20) | 1 (5) | 0.367 |
 Platelet count, <100 × 109/L | 0 (0) | 1 (5) | 1 |
 Hemoglobin, <115 g/L | 1 (20) | 4 (20) | 1 |
 Hypersensitive C-reactive protein, >6 mg/L | 5 (100) | 6 (30) | 0.009 |
 Procalcitonin, >0.05 ng/mL | 4 (80) | 10 (50) | 0.341 |
 Lactate dehydrogenase, >300 U/L | 3 (60) | 3 (15) | 0.070 |
 D-dimer, >0.5 μg/mL | 3 (60) | 7 (35) | 0.358 |
 Alanine aminotransferase, > 40 U/L | 0 (0) | 2 (10) | 1 |
 Aspartate aminotransferase, >40 U/L | 1 (20) | 5 (25) | 1 |
 Total protein, <60 g/L | 2 (40) | 5 (25) | 0.597 |
 Albumin, <34 g/L | 3 (60) | 12 (60) | 1 |
 Globulin, <26 g/L | 0 (0) | 4 (20) | 0.549 |
 Creatinine, >120 μmol/L | 1 (20) | 4 (20) | 1 |
 Blood urea nitrogen, >8.8 mmol/L | 1 (20) | 3 (15) | 1 |
 CO2 CP, >29 mmol/L | 1 (20) | 3 (15) | 1 |
 Pulse rate, ≥90 bpm | 2 (40) | 7 (35) | 1 |
 Respiratory rate, >20 times/min | 4 (80) | 5 (25) | 0.040 |
 SpO2 (%), <93% | 2 (40) | 4 (20) | 0.562 |
Signs and symptoms | |||
 Body temperature, °C | 5 (100) | 17 (85) | 1 |
 Cough | 4 (80) | 16 (80) | 1 |
 Sputum | 1 (20) | 6 (30) | 1 |
 Hemoptysis | 0 (0) | 1 (5) | 1 |
 Shortness of breath | 3 (60) | 12 (60) | 1 |
 Diarrhea | 0 (0) | 1 (5) | 1 |
 Nausea or vomiting | 0 (0) | 1 (5) | 1 |
 Fatigue | 3 (60) | 7 (35) | 0.358 |
 Myalgia | 0 (0) | 1 (5) | 1 |
 Anorexia | 0 (0) | 1 (5) | 1 |
 Sore throat | 1 (20) | 0 (0) | 0.200 |
 CT findings (bilateral) | 5 (100) | 18 (90) | 1 |
Treatments | |||
 Antibiotics (yes) | 4 (80) | 18 (90) | 0.504 |
 Antiviral therapy (yes) | 3 (60) | 7 (35) | 0.358 |
 Immunomodulators (yes) | 3 (60) | 8 (40) | 0.623 |
 Systemic glucocorticoids (yes) | 4 (80) | 8 (40) | 0.160 |
 Mechanical ventilation | 1 (20) | 1 (5) | 0.367 |
COVID-19 > 30 days | 3 (60) | 7 (35) | 0.358 |
Treatment in intensive care unit | 1 (20) | 1 (5) | 0.367 |
Clinical outcome (death) | 1 (20) | 1 (5) | 0.367 |