Table 4 Pooled temporal analyses of numerical overall and progression-free survival.

From: Benefits of local consolidative treatment in oligometastases of solid cancers: a stepwise-hierarchical pooled analysis and systematic review

Disease/ overall survival

No. of studies

No. of patients

Pooled results, LCT vs. control

(95% confidence interval)

Overall survival

NSCLC

   

1-year OS

11

1112

85.0% (75.8–91.1) vs. 69.4 (54.4–81.1)

2-year OS

10

960

65.2% (55.5–73.7) vs. 37.0 (26.7–48.6)

Colorectal

1-year OS

3

602

88.1% (57.0–97.7) vs. 67.5% (37.7–87.7) 

2-year OS

3

602

66.2% (22.4–93.0) vs. 33.2% (8.8–71.9)

Prostate

3-year OS

2

1477

95.6% (47.1–99.8) vs. 92.6% (41.9–99.5)

SCLC

1-year OS

2

130

60.7% (38.1–79.4) vs. 42.8 (14.7–76.4)

Progression-free survival

NSCLC

1-year PFS

8

891

61.3% (48.7–72.6) vs. 35.7% (23.9–49.6)

2-year PFS

5

636

28.9% (16.8–45.0) vs. 8.6% (5–14.5)

Colorectal

1-year PFS

2

372

60.2% (50.2–69.4) vs. 29.5% (14.2–51.4)

2-year PFS

2

372

35.7% (26.9–45.6) vs. 10.5% (2.5–34.7)

Prostate

1-year PFS

5

1095

82.7% (70.6–90.5) vs. 71.3% (44.3–88.5)

2-year PFS

5

1095

61.7% (42.8–77.6) vs. 45.9% (24.7–68.6)

SCLC

1-year PFS

2

130

30.9% (17.2–49.2) vs. 16.6% (8.0–31.3)

  1. LCT local consolidative treatment, NSCLC non-small cell lung cancer, OS overall survival, HCC hepatocellular carcinoma, SCLC small cell lung cancer, PFS progression-free survival.