Fig. 1: Splicing landscape of 18 TSGs in healthy controls. | npj Precision Oncology

Fig. 1: Splicing landscape of 18 TSGs in healthy controls.

From: Splicing profile by capture RNA-seq identifies pathogenic germline variants in tumor suppressor genes

Fig. 1

a–c Histogram of control samples by ethnicity, age, and gender. d Violin plot indicating median number of splicing events detected at ≥5% PSI with coverage ≥50× for each reported ethnicity. T test p values between neighboring distributions are shown. All other pairwise t test p values were also non-significant (data not shown). e Hierarchical clustering of PSI for splicing events with PSI >1 in at least 150 individuals, assigning PSI to zero if no event was called. Samples (columns) are labeled by batch, age range, gender, and ethnicity.

Back to article page