Fig. 7: A complex host-microbe network in the cervicovaginal microenvironment. | npj Precision Oncology

Fig. 7: A complex host-microbe network in the cervicovaginal microenvironment.

From: Vaginal microbiota, genital inflammation, and neoplasia impact immune checkpoint protein profiles in the cervicovaginal microenvironment

Fig. 7

Venn (a) and network (b) diagrams summarize the results of this study and depict immune checkpoint proteins significantly elevated in patients with invasive cervical carcinoma when compared with HPV-negative controls (indicated in pink); immune checkpoint proteins significantly correlated to genital inflammatory scores (indicated in purple); and immune checkpoint proteins significantly correlated to vaginal microbiota structure (indicated in green). The network diagram also shows correlations of immune checkpoint proteins to other immune checkpoint proteins. Solid and dotted line indicate positive or negative relationships, respectively.

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