Fig. 5: Pathway enrichment in dexamethasone-resistant ALL patient samples.
From: The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia
Pathway enrichment in dexamethasone-resistant ALL patient samples was analyzed using GSEA. a Hallmarks and b Oncogenic signatures gene sets were used for pathway enrichment analysis. c Upregulated and downregulated genes in dexamethasone-resistant ALL patient samples were determined by SAM. The bar graph shows selected top-listed genes. All the upregulated and downregulated genes are included in supplementary table T2. d The enrichment of KEGG cytokine and cytokine receptor interaction pathway in dexamethasone-resistant ALL patient samples was determined by GSEA. e, f SUP-B15 and TANOUE cells were lysed. Lysates were analyzed by SDS-PAGE and western blotting using specific antibodies as labeled. Blots shown in each panel were from the same experiment and processed similarly.
