Table 1 Clinical features of patients with angiosarcoma included in the cohort.

From: Clinical implications of systemic and local immune responses in human angiosarcoma

Clinical characteristics

n

Total number of patients

150 (100%)

Sex

 Male

94 (62.7%)

 Female

56 (37.3%)

Age at diagnosis (years)

 Median (range)

67 (26–104)

 > 65

83 (55.3%)

 ≤ 65

67 (44.7%)

Ethnicity

 Chinese

124 (82.7%)

 Other

26 (17.3%)

Performance status (ECOG score)

 0

70 (49.0%)

 1

52 (36.4%)

 2

11 (7.7%)

 3

6 (4.2%)

 4

4 (2.8%)

Cardiovascular risk factors

 Present

90 (60.0%)

 Absent

60 (40.0%)

Primary tumor site

 Head & neck

88 (58.7%)

  Scalp

 72 (48%)

  Non-scalp

 16 (10.7%)

 Breast

13 (8.7%)

 Limb/trunk

13 (8.7%)

 Other

36 (24%)

Etiology

 Primary

132 (88.0%)

 Secondary

18 (12.0%)

 

 Radiation (n = 8)

 

 Chronic lymphedema (n = 3)

 

 Thrombosed arteriovenous fistula (n = 3)

 

 Organ transplant (n = 1)

 

 Neurofibromatosis Type 1 (n = 1)

 

 Li-Fraumeni syndrome (n = 1)

 

 Xeroderma pigmentosum (n = 1)

Epithelioid component

 Present

59 (51.3%)

 Absent

56 (48.7%)

Distant metastasis at diagnosis

 Present

60 (40.0%)

 Absent

90 (60.0%)

  Curative surgery

 48 (32.0%)

  Other*

 42 (28.0%)

  1. Hypertension, hyperlipidemia, diabetes mellitus, ischemic heart disease, cerebrovascular disease.
  2. Sites include liver (n = 13), spleen/heart/peritoneum (n = 3 each), pleura/bone/small bowel/prostate (n = 2 each), brachial plexus/kidney/ovary/vagina (n = 1 each), unknown (n = 2).
  3. *Surgically unresectable (n = 35), medical/other reasons (n = 7).
  4. Data unavailable for ECOG score (n = 7), histomorphology (n = 35).