Fig. 6: Five immune checkpoints expression heterogeneity in tumor stroma of primary lesions and BM.

a Representative images of MIF of immune checkpoints expression including PD-1, PD-L1, TIM-3, LAG-3, and CD73. MFI comparison of PD-L1 (b), PD-1 (c), LAG-3 (d), TIM-3 (e), and CD73 (f) cells between primaries and BM. MFI mean fluorescence intensity.