Fig. 3: Fundus photos of the left eye are shown alongside matched genomic profiles.
From: Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy
A The left eye demonstrated a high tumor fraction (TFx) of 84.54% during intravitreal chemotherapy corresponding to the active vitreous seeds seen clinically. B Enucleation was performed due to an active retinal recurrence shown in the fundus photo. Immediately after enucleation of the left eye, TFx from AH was 98.09%. C AH obtained immediately the following enucleation and matched tumor tissue demonstrated 99.79% concordance in the presence of genomic alterations.
