Table 5 Association between polygenic risk scores and four nested outcomes in the VIP and MDC cohorts separately.
From: Prostate cancer polygenic risk score and prediction of lethal prostate cancer
VIP cohort | MDC cohort | |||
|---|---|---|---|---|
Event N | Modified PRACTICAL riska | Event N | Modified PRACTICAL riska | |
Prostate cancer | 2412 | 1.69 (1.60, 1.79) | 1576 | 1.25 (1.11, 1.41) |
Intermediate and high-risk prostate cancer | 1167 | 1.74 (1.64, 1.84) | 1120 | 1.26 (1.11, 1.43) |
High-risk prostate cancer | 552 | 1.68 (1.54, 1.83) | 625 | 1.18 (1.02, 1.36) |
Prostate cancer metastasis or death | 308 | 1.65 (1.48, 1.84) | 371 | 1.25 (1.10, 1.41) |
