Fig. 1: The combination immunotherapy of Neo-MoDC vaccine and nivolumab mediated rapid complete regression. | npj Precision Oncology

Fig. 1: The combination immunotherapy of Neo-MoDC vaccine and nivolumab mediated rapid complete regression.

From: Durable complete response to neoantigen-loaded dendritic-cell vaccine following anti-PD-1 therapy in metastatic gastric cancer

Fig. 1: The combination immunotherapy of Neo-MoDC vaccine and nivolumab mediated rapid complete regression.The alternative text for this image may have been generated using AI.

a Treatment schema. Cyclophosphamide (CTX) 300 mg/m2 was administrated two days before the first dose of Neo-MoDC vaccine. b The changes of tumor marker CA125 during the treatment. c Tumor lesions shrank during treatment and the follow-ups. Two vertical dotted lines denote day 126 (lymph node < 10 mm) and day 231 (tumor complete regression by PET/CT). d PET/CT image of right ovary (Left panels, yellow circles) and PET image (right panel) show complete regression on day 231. e Representative images of targeted tumor lesions during treatment. Yellow arrows represent targeted tumor lesions. Blue arrows denote complete regressed tumor lesions.

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