Fig. 7: Cluster importance comparison among lung AD and SCC.

The first two columns are squamous cell carcinoma cases (First and second columns are low and high-risk respectively). The last two columns are adenocarcinoma cases (Third and fourth columns are low and high-risk respectively). The first row represents the H&E WSI samples for lung AD (A, B) and SCC (C, D). Second row represents the plotting of cluster position that were assigned as ‘obstructive’ by the TIL model (MSCC) for (E, F) lung SCC and TIL model (MAD) for (G, H) lung AD. Third row represents the plotting of cluster position that were assigned as ‘constructive’ by the TIL model (MSCC) for (I, J) lung SCC and TIL model (MAD) for (K, L) lung AD model. For the low-risk samples (I, K), the influence of ‘constructive’ Cluster C4 around other clusters, is highlighted by the dotted-line region.