Fig. 2: Pancreatic cancer ecotype discovery and survival analysis. | npj Precision Oncology

Fig. 2: Pancreatic cancer ecotype discovery and survival analysis.

From: High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival

Fig. 2: Pancreatic cancer ecotype discovery and survival analysis.The alternative text for this image may have been generated using AI.

A Ecotypes discovered within our pancreatic cancer single-cell RNA-seq dataset (n = 190 K cells) and their association with cell state abundances. B Kaplan–Meier curves showing patient survival in PDAC patients profiled by TCGA, stratified by the dominant ecotype (PE1, PE5, or PE6) measured in surgical tumor resection tissue. C −log2 (p-value) associated with overall survival for each of these pancreatic ecotypes in TCGA. D Fraction of each cell state within each pancreatic ecotype in scRNA-seq expression data.

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