Fig. 2: The margin assessment tool features three panes for modeling the gross specimen, histological assessment of tumor of tumor and mapping histological findings back to the surgical site.

Workflow overview: a gross tissue measurements and inking recommendations are made using the 3D Model Pane, which reconstructs 3D models of tissue from video of tissue rotating around a turntable set up, b rapid margin assessment is accomplished through the Histology Pane, which localizes holes/tears (completeness), tumor, and calculates spatial statistics on ink for orientation (blue is 12 o’clock, red is 6 o’clock), and c Mapping Pane maps margin assessment results to surgical specimen through morphing to user defined surgical tumor map and by leveraging the orientation calculated in the Histology Pane to reorient the results to a format understandable by the surgeon.