Fig. 5: Variation in cancer nuclear size correlates with metrics of genomic instability. | npj Precision Oncology

Fig. 5: Variation in cancer nuclear size correlates with metrics of genomic instability.

From: AI powered quantification of nuclear morphology in cancers enables prediction of genome instability and prognosis

Fig. 5

Standard deviation of cancer cell nuclear area was compared to (a) aneuploidy score and (b) homologous recombination deficiency (HRD) score for BRCA, LUAD, and PRAD. c Receiver operating characteristic (ROC) curves for prediction of whole-genome doublings in BRCA, LUAD, and PRAD. ROCs are shown for the five held-out validation splits; mean AUROC is shown for each cancer type.

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