Fig. 6: Cell-type-specific nuclear morphology enables classification of breast cancer molecular subtypes. | npj Precision Oncology

Fig. 6: Cell-type-specific nuclear morphology enables classification of breast cancer molecular subtypes.

From: AI powered quantification of nuclear morphology in cancers enables prediction of genome instability and prognosis

Fig. 6

One-vs.-all binary classification of breast cancer molecular subtypes (luminal A, luminal B, HER2-like, basal-like, and normal-like)46 was performed using random forest classification on nuHIFs derived from (a) cancer cells, (b) fibroblasts, (c) lymphocytes, and (d) aggregated cell types. Five-fold stratified cross-validation was used, and mean AUROC for each of the iteratively held-out test sets is reported here.

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