Fig. 1: Comprehensive analysis of 18 key HRGs in LUAD. | npj Precision Oncology

Fig. 1: Comprehensive analysis of 18 key HRGs in LUAD.

From: XRCC2 driven homologous recombination subtypes and therapeutic targeting in lung adenocarcinoma metastasis

Fig. 1: Comprehensive analysis of 18 key HRGs in LUAD.

a The GSEA algorithm showed that the DNA recombination, homologous recombination, and recombinational repair pathways were significantly enriched in LUAD. b Comparative analysis of expression levels for the 18 HRGs between tumor and normal tissues. c Elevated expression of 14 HRGs in paired samples. d Prognostic analysis of 18 HRGs using the log-rank test for survival curves. e Functional enrichment network of 18 HRGs elucidated through the ClueGO algorithm. f Exploration of mutation frequency and types for each HRG in LUAD patients. The boxplots show the distribution of expression levels for distinct groups. The center line represents the median. The box boundaries represent the interquartile range. The whiskers representing the minimum and maximum values.

Back to article page