Fig. 7: XRCC2 promoted the migration and invasion of lung cancer cells.

a Scratch experiments after XRCC2-shRNA transfection in A549 cells, recording cell wound healing at 0, 12 h, 24 h, and 36 h. b Wound healing assessment in PC9 cells transfected with XRCC2 overexpression plasmid, observed at 0, 12 h, 24 h, and 36 h in scratch experiments. c Transwell invasion assay assessing invasion ability of A549 cells, with crystal violet staining and counting after 24 h of chamber culture. d Transwell invasion assay evaluating invasion ability of PC9 cells, with crystal violet staining and counting after 24 h of chamber culture. e Comparison of metastatic nodules in the lung tissue of nude mice between XRCC2 knockdown and control groups. f HE staining to determine the number of lung metastasis nodules in the two groups of nude mice. g, h Removal of liver and spleen tissues from nude mice, recording and comparing the number of tumor metastasis nodules. **p < 0.01, ***p < 0.001. The error bars represent the SEM.