Fig. 6: Classification results of RF, kNN, and NN model for grade 4 glioblastoma, IDH wildtype, H3.3 G34 mutant (GBM, G34) methylation class at different contamination levels. | npj Precision Oncology

Fig. 6: Classification results of RF, kNN, and NN model for grade 4 glioblastoma, IDH wildtype, H3.3 G34 mutant (GBM, G34) methylation class at different contamination levels.

From: Comparison of DNA methylation based classification models for precision diagnostics of central nervous system tumors

Fig. 6

a, d, g Density plots of all calls (blue curve) and calls over the 0.9 clinical threshold (orange curve) at each possible methylation family predicted by RF, kNN, and NN when the ground truth is GBM, G34 at different fractions of control tissue contamination. b, e, h Box plots show the score distribution for each methylation family predicted by RF, kNN, and NN models. c, f, i Prediction accuracy of each classifier at each purity level.

Back to article page