Fig. 4: TP53TG1 promotes glioma proliferation and EMT process in vitro. | npj Precision Oncology

Fig. 4: TP53TG1 promotes glioma proliferation and EMT process in vitro.

From: Methionine deprivation inhibits glioma proliferation and EMT via the TP53TG1/miR-96-5p/STK17B ceRNA pathway

Fig. 4

A, B Cell viability of LN229 and U251 cells is assessed using the MTT assay. C–F Glioma cell proliferation is evaluated using the colony formation and EdU assays. The scale bar represents 100 μm. G, H Glioma cell migration and invasion abilities are determined using the transwell assay. The scale bar represents 100 μm. I, J The protein levels of EMT markers (N-cadherin, E-cadherin, and vimentin) in LN229 glioma cells when TP53TG1 is either overexpressed or knocked down. Error bars represent mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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